Wrinkle Relaxers
Muscle-relaxing injections for aesthetic and medical concerns
Muscle relaxant injections temporarily relax specific targeted muscles. By easing the muscle activity involved, they help soften the appearance of expression lines, and can also address certain medical needs where excessive muscle activity becomes uncomfortable. At Dermapure, it all begins with a personalized medical consultation with our medical team to assess whether this approach is right for your needs and to discuss your goals, the targeted area, the expected results, the recovery and the possible side effects.
Aesthetic Concerns
On the aesthetic side, wrinkle relaxers target the specific muscles responsible for expression lines, helping to gradually soften their appearance. The area treated and placement of injections are tailored to your anatomy and to what you would like to achieve.
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Forehard Injections
The forehead is one of the first areas where horizontal expression lines develop with repeated muscle activity. Forehead injections target the muscles responsible to soften the appearance of these lines, with placement personalized to your facial expressions and anatomy.
Crows Feet Injections
Fine lines around the outer corners of the eyes, often called crow's feet, develop from repeated muscle movement during smiling, squinting and other everyday expressions. Crow's feet injections target these muscles to soften the lines that fan outward from the eye area.
Brow Lift Injections
For those interested in a subtle lift of the brow line without surgery, brow lift injections relax the muscles that pull the brow downward, allowing it to settle in a slightly elevated position. The technique is personalized to your natural brow shape.
Nefertiti Neck Lift
The Nefertiti Neck Lift targets specific muscles along the neck and jawline to support a more defined contour of the lower face and upper neck. The placement of injections is adapted to your individual neck anatomy and aesthetic goals.
Lip Flip
The Lip Flip relaxes the muscle around the upper lip, allowing it to gently roll outward and increase its visible border. It can also address a gummy smile, where the upper gums show more prominently when smiling, with placement adapted to your anatomy.
Soft Lift
Soft Lift combines two complementary injectable approaches in a single session. Dermal fillers restore volume and refine facial contour, while complementary injections relax targeted muscles to soften expression lines such as forehead lines, frown lines or crow's feet, all coordinated within one personalized plan.
Micro-Injections
Micro-Injections deliver a customized blend of hyaluronic acid and complementary ingredients just beneath the skin's surface using an applicator with ultra-fine needles, at a consistent depth of about 0.6 mm. The treatment targets dullness, enlarged pores and surface hydration.
Scrotox
Scrotox is a non-surgical in-clinic option for men interested in smoothing fine lines and easing muscle activity in the scrotal area. The treatment may also help reduce localized sweating in this region, with placement and dosage personalized during consultation with our medical team.
Therapeutic Applications
Beyond expression lines, wrinkle relaxers are also used in medicine to ease conditions linked to muscle overactivity. Each of these indications begins with a thorough medical evaluation by our medical team before treatment is initiated.
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Masseter Injections (Bruxism)
Masseter injections target the jaw muscle to relieve the tension associated with bruxism (teeth grinding) and temporomandibular joint discomfort. With repeated treatments, the muscle may also gradually reduce in volume, which can change the contour of the lower face.
Hyperhidrosis Injections
Hyperhidrosis injections address excessive sweating in areas such as the underarms, palms or feet. The treatment targets the nerve signals that activate sweat glands, with the placement adapted to the specific affected zones and discussed during your consultation.
Chronic Migraine Injections
For adults living with chronic migraine, targeted injections can be part of a medical plan to help reduce the frequency or intensity of migraine episodes. This indication requires a thorough medical evaluation by our medical team before treatment is initiated.
Trapezius injections
Trapezius injections target the trapezius muscle, at the base of the neck and shoulders, to relieve tension related to repetitive movements or excessive muscle activity. With repeated sessions, the muscle may also gradually reduce in volume, which can change the contour of the shoulders and neckline.
Calf injections
Calf injections target the calf muscles when excessive muscle activity or significant muscle volume affects comfort or the shape of the leg. With repeated sessions, the muscle may gradually reduce in volume, which can change the contour of the lower leg.
Injections For Erectile Dysfunction
For adults experiencing erectile dysfunction, targeted injections may be considered as part of a medical approach to support erectile function. This emerging indication uses muscle-relaxing injections in the penile area to address smooth muscle activity, with a thorough medical evaluation by our medical team required before treatment.
Follow-Up & Maintenance
Wrinkle relaxer results are not permanent. Effects gradually fade as muscle activity returns over time. The timing of follow-up sessions varies depending on the area treated, the dose used and individual factors. Our medical team will define a realistic schedule with you during your consultation.
Side Effects & Contraindications
As with any medical injectable, wrinkle relaxers can cause side effects. Most are mild and temporary, while some less common reactions deserve attention.
- Common side effects: Minor swelling, redness, tenderness or bruising at the injection site, occasionally accompanied by a temporary headache, are common in the first few days following treatment. These typically resolve on their own within several days.
- Less frequent side effects: Temporary asymmetry, drooping (such as eyelid ptosis), or weakness in nearby muscles can occur. Allergic reactions are rare but possible.
- Who should avoid wrinkle relaxers: wrinkle relaxer injections are not recommended during pregnancy or breastfeeding, in patients with certain neuromuscular disorders, in those with active skin infections at the planned injection site, or in those with a known hypersensitivity to any component of the product.
Frequently Asked Questions
Do GLP-1 medications affect wrinkle relaxer treatments?
With the rise of GLP-1 medications used for weight loss and metabolic conditions, the interaction with wrinkle relaxer treatments is increasingly being studied. A recent computational modelling study (Toxicon, 2026), based on simulated patient data, suggested that GLP-1 use may be associated with shorter duration of effect and earlier signs of wear-off for wrinkle relaxers, in both aesthetic and therapeutic applications. The authors proposed several possible mechanisms, including changes in protein targets, lean muscle loss and broader metabolic effects. It is important to note that this was a simulation study and not based on real patient data, and clinical validation is still needed. In practice, wrinkle relaxer treatments can still be effective in patients receiving GLP-1 medications, although dosing or frequency may need to be adjusted. If you are taking or considering a GLP-1 medication, share this information with our medical team during your consultation so it can be factored into your treatment plan.
How much do wrinkle relaxers cost?
The cost varies by the area treated, the dose used and the treatment plan. The best way to get an accurate estimate is to book a personalized consultation, during which our medical team will discuss the recommended approach and the associated cost.
How long does a wrinkle relaxer appointment take?
The appointment typically takes between 15 and 30 minutes, depending on the area treated and the number of zones addressed. A medical consultation is required before the first treatment at Dermapure.
What are the risks of wrinkle relaxer injections?
As with any medical injectable, wrinkle relaxers carry some risks. Common reactions include temporary swelling, redness, tenderness or bruising at the injection site, and occasional mild headache. Less frequent reactions include temporary asymmetry, drooping or weakness in nearby muscles. Our medical team will review your medical history, the full list of risks and the signs that should prompt you to contact the clinic during your consultation.
Do wrinkle relaxer injections hurt?
Discomfort during treatment is typically minimal. A fine needle is used, and tolerance varies from one person to the next. A topical anesthetic can be applied beforehand if needed.
When will I see results from wrinkle relaxer injections?
The onset of visible effects varies by the area treated and individual factors. Our medical team will discuss expected timing during your consultation.
How long do wrinkle relaxer results last?
Results typically last 3 to 4 months on average, although this can vary depending on the area treated, the dose used and individual factors such as metabolism and muscle strength. Our medical team will define realistic expectations and a follow-up schedule with you during your consultation.
What factors influence how long wrinkle relaxer results last?
Several factors can influence duration, including the area treated, the dose used, muscle strength and individual metabolism. Lifestyle factors such as intense physical activity may also play a role. Our medical team will discuss this with you during your consultation.
When can I return to my normal activities after wrinkle relaxer injections?
Most patients return to their regular activities immediately following treatment. Avoiding strenuous exercise and lying flat for a few hours after the session is generally recommended.
Can wrinkle relaxers be combined with dermal fillers?
Yes. Wrinkle relaxers and dermal fillers address different concerns and can be combined within a personalized plan. Wrinkle relaxers ease muscle activity to soften expression lines, while dermal fillers restore volume and refine contours. Our medical team will assess whether combining the two is appropriate for your goals.
What is the difference between a wrinkle relaxer and a dermal filler?
A wrinkle relaxer works by temporarily relaxing the muscles that create expression lines, easing the movement responsible for those lines. A dermal filler restores lost volume directly beneath the skin to refine contours and soften static lines, and can also support skin hydration. The two address different concerns and can be combined within a personalized plan, depending on your goals.
Why Choose Dermapure
At Dermapure, a wrinkle relaxer is treated as a medical act, never a quick fix. Every treatment is led by our medical team and guided by our Triangle of Care, where injectable treatments, energy-based devices and medical-grade skincare come together in one plan shaped around your anatomy and your goals. Their expertise in the anatomical, technical and aesthetic side of each treatment informs every decision. And as the largest network of medical aesthetic clinics in Canada, our experts continually learn from one another and share their knowledge and clinical experience, so your plan benefits from the collective expertise of teams across the country.
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