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Platelet-Rich Fibrin (PRF) Edmonton
PRF, or platelet-rich fibrin, is a regenerative non-surgical treatment offered at our Dermapure clinics in Edmonton. After a small blood draw, the sample is processed at low speed in-clinic to concentrate platelets, white blood cells and natural growth factors into a soft fibrin matrix, delivered to the skin or scalp through microinjections, microneedling-assisted application or other targeted delivery methods, depending on the treatment plan.
PRF can support skin renewal on the face (including the under-eye area), the cheeks, smile lines and acne scars, and is also used on the scalp to support follicle activity. Because PRF is processed without anticoagulants, the fibrin matrix releases growth factors gradually over several days, with progressive results. The treatment may be received on its own across a series of sessions, or paired with complementary in-clinic options such as RF microneedling, dermal fillers, exosome therapy or medical-grade skincare protocols.
Because every patient’s skin, concerns and medical history are different, PRF at our Dermapure clinics in Edmonton always begins with a personalized consultation with a physician or healthcare professional. Together, you will assess whether PRF is the most appropriate option for you and discuss a realistic treatment plan, the expected results and the possible side effects. Book your personalized consultation with our team in Edmonton.
Local clinics offering Platelet-Rich Fibrin (PRF)
Dermapure Edmonton South (Lucere)
How it works
After a small blood draw, your sample is placed in a centrifuge that spins slowly. This gentle process separates and concentrates the most healing parts of your blood such as platelets, white blood cells and growth factors into what we call platelet-rich fibrin (PRF). This golden, gel-like substance is then applied to the skin using microneedling or small injections.
Once under the skin, PRF slowly releases natural growth factors over several days. These growth factors help boost collagen production, improve blood flow and encourage your skin cells to repair and renew themselves. The result is smoother, firmer and more even-looking skin that improves gradually and naturally over time.
Compared to platelet-rich plasma (PRP), PRF works more slowly but lasts longer. It does not contain any additives or anticoagulants, which allows it to work in harmony with your body for soft and natural-looking results.
What to Expect During Your Session
Personalized Consultation
Pre-Treatment Photography
Blood Collection & PRF Preparation
Skin Cleansing & Disinfection
PRF Application
Follow-Up & Maintenance
PRF delivers progressive and long-lasting results. In most cases, a series of 2 to 4 sessions spaced several weeks apart is recommended to activate optimal skin or hair regeneration. Your provider will determine the ideal number and frequency of sessions based on your skin condition and goals. To enhance outcomes, PRF can be combined with other aesthetic treatments such as RF microneedling or dermal fillers. These combinations can support deeper collagen stimulation and restore volume more effectively. Your provider will tailor a treatment plan that aligns with your skin’s needs and long-term objectives.
Contraindications
PRF is a safe treatment derived from your own blood, but it may not be suitable for everyone. Individuals with certain medical conditions or blood disorders may not be eligible for this procedure. Contraindications may include active infections or inflammatory skin conditions in the treatment area, blood clotting disorders or anticoagulant therapy, autoimmune diseases affecting skin healing and pregnancy or breastfeeding. During your consultation, your provider will review your medical history to ensure that PRF is appropriate and safe for you.
Frequently Asked Questions
How does PRF compare to exosome treatments?
PRF and exosome treatments both aim to support skin regeneration, but they work differently. PRF is fully autologous, meaning it comes from your own blood and contains platelets, white blood cells and natural growth factors. Exosomes, on the other hand, are lab-produced and typically derived from stem cells. While exosomes may offer targeted signals for cell repair, PRF provides a broader mix of healing components and integrates more naturally with your body. Many patients prefer PRF for its safety, biocompatibility and proven ability to stimulate collagen and tissue renewal over time.
